Systems biology


WIRED Systems biology looks at the connections between components in cells. [C&EN 81(20): 45-55, 2003]

Systems biology and system theory

Hybrid systems

  • De Jong, Helix Bioinformatics, INRIA, Grenoble (Montbonnot) (

  • Pappas / Kumar, Biocomputation group, University of Pennsylvania, Pennsylvania ( Collaboration with Luc Habets (CWI / TU/e).

  • Tomlin, Hybrid Systems Laboratory, Dept. of Aeronautics and Astronautics, Stanford University, Stanford (

  • Systems Biology, University of Stuttgart: Gilles (Institute for System Dynamics and Control Engineering), Allgöwer (Institute for Systems Theory in Engineering), (

Parameter identification


System identification (parameter estimation, databased modeling)




Databases and software

Modeling and analysis of biochemical network models

Biomodels Databases

Pathway Databases

Kinetic information

Visualizing molecular interaction networks

Network reconstruction / reverse engineering




For comments on this page, please send an email to n.a.w.v.riel

Last update: June 2008

Systems Biology in the Netherlands

Eindhoven Biomedical  Systems Biology


Centre for Medical Systems Biology, Leiden (


Molecular Cell Physiology, VU


Mathematics and Computation for the Systems Biology of Cells, UvA


Systems biology course, Wageningen University (


Theorethical Biology/ Bioinformatics Utrecht (


Centre for Molecular and Biomolecular Informatics, Nijmegen (


Netherlands Bioinformatics Centre


Systems Biology Center Delft, Information and communication theory group, TUD ( (old)


Netherlands’ Platform for System Biology (old)


European Systems Biology (old)

» Software and models
» Eindhoven Biomedical Systems Biology